Meta example: Christine Cavanaugh, Chuckie's original voice actress, died in December 22, 2014 of Leukemia. Shortly after news of her death broke, The '90s Are All That on TeenNick aired a marathon of Chuckie episodes in her memory.
- Similarly, Joe Alaskey, the second voice of Grandpa Lou, died in February 3, 2016 from unknown cancer complications.
- His first voice, David Doyle, died midway through the series. The episode "Lady Luck" ends with a dedication to him.
- In August 19, 2016, Jack Riley, the voice of Stu Pickles, died from pneumonia.
- In November 25, 2016, Ron Glass, the voice of Randy Carmichael, died from respiratory failure.